KPTI — Karyopharm Therapeutics Inc.

KPTIKaryopharm Therapeutics Inc.

NAS · US · Healthcare · Biotechnology · karyopharm.com

8.900USD+9.07%Mkt Cap: 203.06M USDP/E: —Last update: 2026-05-26

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. …

Industry Peers

Biotechnology

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Indicators:|

Key Statistics

Company

Market Cap203.06M USD

Enterprise Value387.58M USD

Revenue (TTM)151.12M USD

Gross Profit140.12M USD

Net Income (TTM)-196.04M USD

Revenue/Share10.55 USD

Last Price8.900 USD

Fiscal Year EndDec 2025

MR QuarterMar 2026

Employees228

CountryUS

SectorHealthcare

IndustryBiotechnology

ISINUS48576U1060

Valuation

P/E (Trailing)—

P/E (Forward)-1.65

PEG—

EV/EBITDA-4.62

EV/Revenue2.56

P/S1.21

P/B-0.50

EPS (TTM)-16.40

EPS (Forward)-4.89

52W Range

3.65072% of range10.99

52W High10.99 USD

52W Low3.650 USD

Profitability

Gross Margin95.93%

Oper. Margin-76.31%

EBITDA Margin-55.53%

Profit Margin-134.21%

ROE66.92%

ROA-180.82%

Growth

Revenue Growth16.80%

Earnings Growth—

Cash Flow & Leverage

Operating CF-75.37M USD

CapEx (TTM)—

FCF Margin—

FCF Yield—

Net Debt205.88M USD

Net Debt/EBITDA-2.45

Balance Sheet

Debt/Equity-0.80

Current Ratio—

Quick Ratio—

Book Value/Sh-15.9970 USD

Cash/Share4.030 USD

Dividends

Fwd Div Rate—

Trail. Div Rate0.0000 USD

Div. Yield—

5Y Avg Yield—

Payout Ratio0.00%

Ex-Div Date—

Pay Date—

Splits

Last Split1:15

Split DateFeb 26, 2025

Analyst Consensus

Rating1.6 (Buy)

Target (Mean)13.50 USD

Target Range7.000 USD – 16.00 USD

# Analysts6

Ownership

Shares Out.22.66M

Float15.22M

Insiders4.48%

Institutions78.02%

Short Interest

Short Ratio10.3d

Short % Float23.59%

Short % Out.23.47%

Shares Short5.29M

Short (prev mo.)5.46M

Technical

SMA 507.874 (+13.0%)

SMA 2006.957 (+27.9%)

Beta0.81

S&P 52W Chg28.31%

Avg Vol (30d)431.69K

Avg Vol (10d)615.80K

Technical Indicators

RSI (14)—

MACD—

MACD Signal—

MACD Hist.—

BB Upper—

BB Middle—

BB Lower—

BB Width—

ATR (14)—

Vol Ratio (20d)—