A landmark trial success for Moderna and Merck's cancer vaccine has strengthened the case for Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP), the immuno-oncology company developing a rival melanoma treatment, according to one broker covering the sector's innovative small-caps. Merck and...

A rally in government bonds eases pressure on equities

Empire Metals Ltd (AIM:EEE, OTCQX:EPMLF) has upgraded its Pitfield project in Western Australia to 8.16 billion tonnes, confirming it as the world's largest titanium resource. That includes a first Measured Resource of 374 million tonnes at a solid 5.8% grade. Vast Resources PLC (LSE:VAST, FRA:D9A) has completed its takeover of Gulf International Minerals, adding a producing gold and silver mine in Tajikistan. It's also raised around £7.5 million to fund the next stage of development following its re-admission to London's AIM. Rockfire Resources PLC (LSE:ROCK) has hit fresh high-grade zinc and germanium at its Molaoi deposit in Greece. The best intersection came in at 6.2% zinc and over 15 grams per tonne germanium. Oxford Nanopore Technologies PLC ( LSE:ONT) jumped 4% after setting a target of $700 million in annual revenue by 2030. It's also aiming to break even on adjusted earnings by 2027. Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP) has won UK approval to run a late-stage trial of its melanoma drug iSCIB1+. That follows FDA approval back in January, with more applications now under way. Follow us and subscribe on YouTube, our social channels, and on proactiveinvestors.co.uk.

Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP), the cancer immunotherapy developer, has won UK regulatory approval to run a late-stage trial of its lead drug in advanced melanoma. The Medicines and Healthcare products Regulatory Agency (MHRA) has granted a clinical trial authorisation...

Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP) confirmed the UK leg of its equity funding has raised gross proceeds of £15.7 million after strong retail demand prompted the cancer immunotherapy developer to increase the size of its retail offer. The retail offer raised £2.7...

Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP) saw its shares drop 27% this week, but the movement obscures the real story, which is a largely positive one for investors. It may take the market a while to process some transformational changes that will see the oncology research...

Neuphoria Therapeutics (NEUP) and Scancell Holdings said Thursday they have agreed to an all-stock m

Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP), the Oxford-based cancer immunotherapy developer listed on London's junior AIM market, has agreed an all-share merger with US biotech Neuphoria Therapeutics that will give it a Nasdaq listing and access to American investors. The combined...

EnergyPathways PLC (AIM:EPP) has launched Front End Engineering and Design for what could become the world's largest compressed air energy storage project. Pre-FEED work with Siemens Energy confirmed the project's viability, with a £15 million financing package now in place to fund the next phase. Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP) has secured FDA Fast Track Designation for its lead cancer drug iSCIB1+ in advanced melanoma. Phase II trial data shows 77% progression-free survival at 20 months, compared with 43% for the current standard of care. Poolbeg Pharma PLC (AIM:POLB, OTC:POLBF, FRA:POLBF) is advancing partnering talks as interim data from its TOPICAL trial approaches this summer. The company estimates the addressable market for POLB 001 at more than $10 billion, with partner interest increasing as data nears. Santhera Pharmaceuticals (SIX:SANN, OTC:SPHDF, FRA:S3F0) reported revenues up 97% to CHF 77.2 million, well ahead of guidance, driven by strong sales of its Duchenne muscular dystrophy drug AGAMREE. The company expects to reach cash flow breakeven in Q3 2026 without further fundraising. Powerhouse Energy Group PLC (AIM:PHE, FRA:BT81) has won a £260,000 contract with a Welsh battery developer, its first revenue outside its Engsolve engineering arm. The company currently has around ten live enquiries it believes could become revenue-generating projects. Active Energy Group PLC (AIM:AEG, OTCID:AEUSF) says its 8MVA site in the United Arab Emirates will become the first pilot deployment under its proposed Bitdeer collaboration. The site could generate around $300,000 per MVA in annual infrastructure revenue alongside 8.3 Bitcoin per MVA per year. Follow us and subscribe on YouTube, our social channels, and on proactiveinvestors.co.uk.

Panmure Liberum holds its 'buy' rating and 32p target as FDA fast-track status adds regulatory momentum to compelling trial data. Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP) shares rose 5.3% to 13.69p on Tuesday as the cancer immunotherapy developer delivered a double dose of...

The AIM-listed biotech reports 77% progression-free survival at 20 months, well ahead of the standard of care Scancell Holdings PLC (AIM:SCLP, OTC:SCNLF, FRA:SCP), the cancer immunotherapy developer, has secured a Fast Track Designation from the U.S. Food and Drug Administration (FDA) for its...

Trump warned the US would step up strikes on Iran over the next two to three weeks

Sorted Group Holdings (AIM:SORT) saw its share price halve to 10p after announcing plans to sell its main business for just £1. The company will become an AIM cash shell and has six months to make an acquisition or face suspension. Cancer immunotherapy developer Scancell Holdings (AIM:SCLP, OTC:SCNLF, FRA:SCP) has named David Schilansky as interim CFO as its current finance chief prepares to leave. Schilansky has previously raised more than $1 billion for listings on Nasdaq and Euronext, experience that could prove useful as Scancell explores a US listing. Active Energy Group (AIM:AEG, OTCID:AEUSF) has converted £278,200 of loans from its CEO into nearly 400 million new shares. Following the conversion, Paul Elliott will hold just under 9.5% of the company. Finally, 88 Energy (AIM:88E, ASX:88E, OTCQB:EEENF, FRA:POQ) has opened nominations for a director election at its AGM on 26 May in Perth. Candidates have until 13 April to submit their applications. Follow us and subscribe on YouTube, our social channels, and on proactiveinvestors.co.uk.