IONSIonis Pharmaceuticals, Inc.
59.74USD-1.74%Mkt Cap: 9.93B $P/E: —3d ago
Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemi…
Industry Peers
Biotechnology$138.82BUSDP/E 31.9
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$61.34BUSDP/E 39.8
$65.05BUSDP/E 39.6
$57.94BUSD
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$44.89BUSD
$42.36BUSDP/E 67.2
$35.43BUSDP/E 32.6
$31.61BUSDP/E 41.2
$29.28BUSD
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$25.91BUSDP/E 16.2
$20.86BUSDP/E 26.3
$19.26BUSDP/E 26.6
$16.61BUSDP/E 19.6
$16.51BUSDP/E 17.4
$15.93BUSD
$13.40BUSDP/E 17.0
Key Statistics
Company
Market Cap9.93B $
Enterprise Value9.85B $
Revenue (TTM)874.09M $
Gross Profit927.80M $
Net Income (TTM)-381.39M $
Revenue/Share5.359 USD
Last Price59.74 USD
Fiscal Year EndDec 2025
MR QuarterJun 2026
Employees1.5K
CountryUS
SectorHealthcare
IndustryBiotechnology
ISINUS4622221004
Valuation
P/E (Trailing)—
P/E (Forward)-55.72
PEG27.33
EV/EBITDA-17.00
EV/Revenue11.27
P/S11.17
P/B22.13
EPS (TTM)-3.36
EPS (Forward)-1.05
52W Range
41.7140% of range86.74
52W High86.74 USD
52W Low41.71 USD
Profitability
Gross Margin98.31%
Oper. Margin-38.18%
EBITDA Margin-66.30%
Profit Margin-40.41%
ROE-77.98%
ROA-10.82%
Growth
Revenue Growth-40.70%
Earnings Growth—
Cash Flow & Leverage
Operating CF-268.58M $
CapEx (TTM)57.08M $
FCF Margin-39.67%
FCF Yield-3.49%
Net Debt86.67M $
Net Debt/EBITDA-0.15
Balance Sheet
Debt/Equity4.22
Current Ratio7.89
Quick Ratio6.85
Book Value/Sh2.655 USD
Cash/Share12.65 USD
Dividends
Fwd Div Rate—
Trail. Div Rate0.0000 USD
Div. Yield—
5Y Avg Yield—
Payout Ratio0.00%
Ex-Div Date—
Pay Date—
Analyst Consensus
Rating1.8 (Buy)
Strong BuyBuyHoldSellStr. Sell
Target (Mean)88.00 USD
Upside (mean)+47.3%
Target Range60.00 USD – 115.00 USD
$60.00+47.3% to mean$115.00
# Analysts22
Ownership
Shares Out.166.18M
Float164.85M
Insiders0.61%
Institutions110.33%
Short Interest
Short Ratio5.0d
Short % Float17.11%
Short % Out.12.92%
Shares Short21.47M
Short (prev mo.)17.43M
Technical
SMA 5064.29 (-7.1%)
SMA 20074.06 (-19.3%)
Beta0.40
S&P 52W Chg18.16%
Avg Vol (30d)3.76M
Avg Vol (10d)2.18M
Technical Indicators
RSI (14)52.8
MACD-1.0825
MACD Signal-2.3708
MACD Hist.+1.2883
BB Upper60.19 USD
BB Middle55.94 USD
BB Lower51.68 USD
BB Width15.20%
ATR (14)2.244 USD
Vol Ratio (20d)0.97x