IONS Ionis Pharmaceuticals, Inc.
44.16USD+0.36%Mkt Cap: 7.34B $P/E: —1d ago
Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemi…
Industry Peers
Biotechnology$128.08BUSDP/E 29.4
$78.44BUSD
$76.40BUSDP/E 18.4
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$22.27BUSDP/E 30.7
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$22.22BUSD
$15.03BUSDP/E 17.5
$15.01BUSDP/E 15.8
$14.48BUSDP/E 18.4
$14.32BUSD
Key Statistics
Company
Market Cap7.34B USD
Enterprise Value7.40B USD
Revenue (TTM)874.09M USD
Gross Profit927.80M USD
Net Income (TTM)-381.39M USD
Revenue/Share5.36 USD
Last Price44.16 USD
Fiscal Year EndDec 2025
MR QuarterJun 2026
Employees1.5K
CountryUS
SectorHealthcare
IndustryBiotechnology
ISIN—
Valuation
P/E (Trailing)—
P/E (Forward)-39.56
PEG27.33
EV/EBITDA-12.77
EV/Revenue8.46
P/S8.37
P/B16.57
EPS (TTM)-3.48
EPS (Forward)-1.11
52W Range
42.633% of range86.74
52W High86.74 USD
52W Low42.63 USD
Profitability
Gross Margin98.31%
Oper. Margin-38.18%
EBITDA Margin-66.30%
Profit Margin-40.41%
ROE-77.98%
ROA-10.82%
Growth
Revenue Growth-40.70%
Earnings Growth—
Cash Flow & Leverage
Operating CF-268.58M USD
CapEx (TTM)57.08M USD
FCF Margin-39.67%
FCF Yield-4.73%
Net Debt86.67M USD
Net Debt/EBITDA-0.15
Balance Sheet
Debt/Equity4.22
Current Ratio7.89
Quick Ratio6.85
Book Value/Sh2.65 USD
Cash/Share12.65 USD
Dividends
Fwd Div Rate—
Trail. Div Rate0.00 USD
Div. Yield0.00%
5Y Avg Yield—
Payout Ratio0.00%
Ex-Div Date—
Pay Date—
Analyst Consensus
Rating1.8 (Buy)
Strong BuyBuyHoldSellStr. Sell
Target (Mean)83.64 USD
Upside (mean)+89.4%
Target Range54.00 USD – 105.00 USD
54.00+89.4% to mean105.00
# Analysts22
Ownership
Shares Out.166.18M
Float164.82M
Insiders0.61%
Institutions110.37%
Short Interest
Short Ratio6.6d
Short % Float16.65%
Short % Out.12.57%
Shares Short20.89M
Short (prev mo.)20.91M
Technical
SMA 5053.41 (-17.3%)
SMA 20070.05 (-37.0%)
Beta0.38
S&P 52W Chg16.45%
Avg Vol (30d)3.58M
Avg Vol (10d)3.58M
Technical Indicators
RSI (14)32.4
MACD-3.3537
MACD Signal-3.5023
MACD Hist.+0.1486
BB Upper56.53 USD
BB Middle47.08 USD
BB Lower37.63 USD
BB Width40.15%
ATR (14)1.990 USD
Vol Ratio (20d)0.65x